alpha-parvin (calponin-like integrin-linked kinase binding protein, CH-ILKBP, PARVA)

Function

• role in regulation of cell adhesion & cytoskeleton organization (putative)
• interacts with integrin-linked protein kinase & actin

Structure

• belongs to the parvin family
• contains 2 CH domains (calponin-homology domains)

Compartment

• cell junction, focal adhesion, cytoplasmic side
• constituent of focal adhesions

Alternative splicing

named isoforms=2

Expression

• widely expressed, with highest levels in heart, skeletal muscle, kidney & liver

More general terms

• parvin (PARV)

Database

• UniProt: http://www.uniprot.org/uniprot/Q9NVD7.html