beta-parvin (affixin, PARVB)
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Function
- role in the regulation of cell adhesion & cytoskeleton organization
- interacts with integrin-linked protein kinase & actin
Structure
- belongs to the parvin family
- contains 2 CH domains (calponin-homology domains)
Compartment
- cell junction, focal adhesion, cytoplasmic side
- constituent of focal adhesions
Expression
- expressed predominantly in heart & skeletal muscle