PDZ & LIM domain protein 3 (actinin-associated LIM protein, alpha-actinin-2-associated LIM protein, PDLIM3, ALP)

Function

• role in the organization of actin filament arrays within muscle cells (putative)
• interacts with ACTN2

Structure

• contains 1 LIM zinc-binding domain
• contains 1 PDZ (DHR) domain

Compartment

• localizes to myofiber Z-lines

Alternative splicing

named isoforms=3

Expression

• isoform 1 is highly expressed in differentiated skeletal muscle
• isoform 2 is heart-specific

More general terms

• PDZ & LIM domain protein

Database

• OMIM: https://mirror.omim.org/entry/605889
• UniProt: http://www.uniprot.org/uniprot/Q53GG5.html