wnt10B proto-oncogene protein (wnt10B, wnt12)

Function

• ligand for members of the frizzled family
• probable developmental protein
• may be a signaling molecule which affects the development of discrete regions of tissues
• likely to signal over only few cell diameters (putative)

Structure

belongs to the Wnt family

Compartment

• secreted, extracellular space, extracellular matrix

Expression

• detected in most adult tissues
• highest levels were found in heart & skeletal muscle
• low levels are found in brain
• infant brain has higher levels of WNT10B than adult brain

More general terms

• wnt proto-oncogene protein or int proto-oncogene protein

Database

• Kegg: http://www.genome.jp/dbget-bin/www_bget?hsa:7480
• UniProt: http://www.uniprot.org/uniprot/O00744.html
• OMIM: https://mirror.omim.org/entry/601906
• Entrez gene: http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&cmd=Retrieve&dopt=Graphics&list_uids=7480