wnt10A proto-oncogene protein

Function

• ligand for members of the frizzled family
• probable developmental protein
• may be a signaling molecule important in CNS development
• is likely to signal over only few cell diameters

Structure

belongs to the Wnt family

Compartment

• secreted, extracellular space, extracellular matrix

Pathology

• defects in WNT10A
  • odontoonychodermal dysplasia
  • Schopf-Schulz-Passarge syndrome

More general terms

• wnt proto-oncogene protein or int proto-oncogene protein

Database

• UniProt: http://www.uniprot.org/uniprot/Q9GZT5.html
• Kegg: http://www.genome.jp/dbget-bin/www_bget?hsa:8032
• OMIM: https://mirror.omim.org/entry/257980
• OMIM: https://mirror.omim.org/entry/606268
• Entrez gene: http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&cmd=Retrieve&dopt=Graphics&list_uids=80326