rab20 proto-oncogene protein; Ras-related protein Rab-20 (RAB20)

Function

plays a role in apical endocytosis/recycling

Structure

belongs to the small GTPase superfamily, Rab family

Compartment

• Golgi
• highly enriched on apical endocytic structures in polarized epithelial cells of kidney proximal tubules (putative)

Expression

• low or absent expression in normal pancreas

Pathology

• stronger expression in 15 of 18 exocrine pancreatic adenocarcinomas (at protein level)

More general terms

• rab subfamily protein

Database

• UniProt: http://www.uniprot.org/uniprot/Q9NX57.html
• Entrez gene: http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&cmd=Retrieve&dopt=Graphics&list_uids=55647
• Kegg: http://www.genome.jp/dbget-bin/www_bget?hsa:55647