rab13 proto-oncogene protein; Ras-related protein Rab-13; cell growth-inhibiting gene 4 protein (RAB13)
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Function
- formation of epithelial tight junctions
- could participate in polarized transport, in the assembly &/or the activity of tight junctions
Structure
belongs to the small GTPase superfamily, Rab family
Compartment
- cell junction, tight junction
- cell membrane; lipid-anchor; cytoplasmic side
- cytoplasmic vesicle membrane; lipid-anchor; cytoplasmic side
- cytoplasmic tight junctions or associated with vesicles scattered throughout the cytoplasm in cells lacking tight junctions
Expression
- detected in several types of epithelia, including intestine, kidney, liver & in endothelial cells
More general terms
References
- ↑ Seabra MC et al Rab GTPases, intracellular traffic and disease Trends in Molecular Medicine 8:23, 2002 PMID: https://www.ncbi.nlm.nih.gov/pubmed/11796263
- ↑ Entrez Gene http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&cmd=Retrieve&dopt=Graphics&list_uids=5872
- ↑ UniProt http://www.uniprot.org/uniprot/P51153.html