rhoD protein; Rho-related GTP-binding protein RhoD; Rho-related protein HP1; RhoHP1 (RHOD, ARHD)

Function

• role in endosome dynamics
• may coordinate membrane transport with function of the cytoskeleton
• role in reorganization of actin cytoskeleton (putative)
• in the GTP-bound form, interacts with DIAPH2 isoform 3

Structure

belongs to the small GTPase superfamily, Rho family

Compartment

• cell membrane; lipid-anchor; cytoplasmic side (putative)

Expression

• heart, placenta, liver, skeletal muscle, & pancreas
• weaker expression in several other tissues

More general terms

• rho subfamily protein

Database

• Entrez gene: http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&cmd=Retrieve&dopt=Graphics&list_uids=29984
• Kegg: http://www.genome.jp/dbget-bin/www_bget?hsa:29984
• OMIM: https://mirror.omim.org/entry/605781
• UniProt: http://www.uniprot.org/uniprot/O00212.html