R-ras proto-oncogene protein (p21 R-ras)

Introduction

Not a 'true' ras protein [p21ras].

Function

• cannot by itself transform cells
• binding to raf1 is presumptive

Structure

• a binding site to an inner mitochondrial membrane & nuclear membrane protein bcl-2, brings into question the cellular compartmentalization of R-ras
• C-terminal CaaX motif

More general terms

• ras subfamily protein

Database

• UniProt: http://www.uniprot.org/uniprot/P10301.html
• OMIM: https://mirror.omim.org/entry/165090