membrane-associated phosphatidylinositol transfer protein 2; phosphatidylinositol transfer protein, membrane-associated 2; PITPnm 2; Pyk2 N-terminal domain-interacting receptor 3; NIR-3 (PITPNM2 KIAA1457 NIR3)

Function

• catalyzes the transfer of phosphatidylinositol & phosphatidylcholine between membranes
• binds Ca+2
• interacts with PTK2B via its C-terminus

Structure

• belongs to the Ptdins transfer protein family, PI transfer class IIA subfamily
• contains 1 DDHD domain

Compartment

intracellular membrane, peripheral membrane

Expression

• expressed in brain, heart, ovary, testis, thymus > small intestine, prostate, pancreas, skeletal muscle, liver, colon, placenta

More general terms

• membrane-associated phosphatidylinositol transfer protein
• phosphoprotein

Additional terms

• phosphatidylinositol (phosphoinositide, 1-phosphatidyl-1D-myo-inositol)

Database

• Entrez gene: http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&cmd=Retrieve&dopt=Graphics&list_uids=57605
• Kegg: http://www.genome.jp/dbget-bin/www_bget?hsa:57605
• OMIM: https://mirror.omim.org/entry/608920
• UniProt: http://www.uniprot.org/uniprot/Q9BZ72.html