Golgin subfamily A member 8B (Golgi autoantigen golgin-6, GOLGA8B)

Function

• may be involved in maintaining Golgi structure

Structure

• extended rod-like protein with coiled-coil domains
  • belongs to the Golga8 family

Compartment

• Golgi, Golgi stack membrane
• peripheral membrane

Alternative splicing

named isoforms=2

Expression

• highly expressed in brain, heart & kidney
• detected at lower levels in liver, thymus, spleen, lung & peripheral blood leukocytes

Genetics

• a family of highly similar proteins (GOLGA8A, GOLGA8B, GOLGA8C, GOLGA8D, GOLGA8E, GOLGA8F, GOLGA8G) are encoded by a repeated region on chromosome 15q11-15q13

More general terms

• Golgin subfamily A (GOLGA)

Database

• UniProt: http://www.uniprot.org/uniprot/A8MQT2.html