uroplakin-3B (uroplakin IIIb, UPIIIb, p35, UPK3B)
Jump to navigation
Jump to search
Function
- component of the asymmetric unit membrane (AUM)
- role in AUM-cytoskeleton interaction in terminally differentiated urothelial cells
- contributes to formation of urothelial glycocalyx which may play a role in preventing bacterial adherence
- forms heterodimer with Uroplakin 1b
Compartment
membrane
- heterodimer formation with Uroplakin 1b required for exit from the endoplasmic reticulum