pannexin-2 (PANX2)

Function

• structural component of the gap junctions
• forms PANX1/PANX2-heteromeric intercellular channels on coexpression in paired Xenopus oocytes
• does not form homomeric channels (putative)

Structure

belongs to the pannexin family

Compartment

• cell membrane; multi-pass membrane protein (putative)
• cell junction, gap junction

Alternative splicing

named isoforms=3

More general terms

• pannexin

Database

• Entrez gene: http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&cmd=Retrieve&dopt=Graphics&list_uids=56666
• Kegg: http://www.genome.jp/dbget-bin/www_bget?hsa:56666
• OMIM: https://mirror.omim.org/entry/608421
• UniProt: http://www.uniprot.org/uniprot/Q96RD6.html