pannexin-1 (PANX1, MRS1, UNQ2529/PRO6028)

Function

• structural component of the gap junctions
• forms homomeric or PANX1/PANX2-heteromeric intercellular channels on coexpression in paired Xenopus oocytes

Structure

belongs to the pannexin family

Compartment

• cell membrane; multi-pass membrane protein (putative)
• cell junction, gap junction

Alternative splicing

named isoforms=2

More general terms

• pannexin

Database

• Entrez gene: http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&cmd=Retrieve&dopt=Graphics&list_uids=24145
• Kegg: http://www.genome.jp/dbget-bin/www_bget?hsa:24145
• OMIM: https://mirror.omim.org/entry/608420
• UniProt: http://www.uniprot.org/uniprot/Q96RD7.html