solute carrier family 25 member 2 (SLC25A2, mitochondrial ornithine transporter 2, ORNT2)

Function

• ornithine transport across inner mitochondrial membrane, from the cytoplasm to the mitochondrial matrix

Structure

• belongs to the mitochondrial carrier family
• contains 3 solcar repeats

Compartment

mitochondrial inner membrane

Expression

• expressed in liver, kidney, pancreas, & cultured fibroblasts

Polymorphism

• variant Cys-159 has a reduced ornithine transport; variant Gly-181 has an increased activity

More general terms

• transmembrane 6 protein
• solute carrier family 25 (SLC25, SLC25A)
• mitochondrial membrane protein

Database

• Kegg: http://www.genome.jp/dbget-bin/www_bget?hsa:8388
• OMIM: https://mirror.omim.org/entry/608157
• UniProt: http://www.uniprot.org/uniprot/Q9BXI2.html