protein kinase G type-2 (PRKG2, cGMP-dependent protein kinase type-2, PRKG2, CGK 2, cGKII)

Function

• binding of cGMP results in enzyme activation

Structure

• belongs to the protein kinase superfamily, AGC Ser/Thr protein kinase family, cGMP subfamily
• contains 1 AGC-kinase C-terminal domain
• contains 2 cyclic nucleotide-binding domains
• contains 1 protein kinase domain

Expression

• highly concentrated in brain, lung & intestinal mucosa

More general terms

• protein kinase G (PKG)
• plasma membrane protein

Database

• Kegg: http://www.genome.jp/dbget-bin/www_bget?hsa:5593
• OMIM: https://mirror.omim.org/entry/601591
• UniProt: http://www.uniprot.org/uniprot/Q13237.html