cadherin-related family member 5; mucin & cadherin-like protein; Mu-protocadherin (CDHR5, MUCDHL, MUPCDH, UNQ2781/PRO7168)

Function

• Ca+2-dependent cell adhesion protein

Structure

• N- & O-glycosylated (putative)
• contains 4 cadherin domains

Compartment

• cell membrane
• single-pass type 1 membrane protein (putative)

Alternative splicing

named isoforms=3

Expression

• highest expression in kidney, liver, colon & small intestine
• expressed in kidney, apically along brush border of proximal convoluted tubule
• not expressed in cortical collecting ducts
• isoform 1 is expressed primarily in adult small intestine & colon
• isoform 2 is highly expressed in fetal liver

More general terms

• protocadherin (PCDH)
• phosphoprotein

Additional terms

• cadherin

Database

• Entrez gene: http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&cmd=Retrieve&dopt=Graphics&list_uids=53841
• OMIM: https://mirror.omim.org/entry/606839
• UniProt: http://www.uniprot.org/uniprot/Q9HBB8.html