Taste receptor type 2 member 2; Bitter taste receptor T2R2 (TAS2R2, T2R2, TAS2R2P)

Function

• bitter taste receptor that detects natural & synthetic bitter compounds

Structure

• belongs to the G-protein coupled receptor T2R family

Compartment

• cell membrane
• multi-pass membrane protein

Polymorphism

• the more common sequence differs from the translation of the reference genome assembly (GRCh38/hg38) due to two-base deletion in the reference genome
• an intact form of this gene is still found in some human populations, such as Adygei (from Eastern Europe), Biaka, & Mbuti Pygmies (both from Africa)

More general terms

• taste receptor, type 2

Database

• UniProt: http://www.uniprot.org/uniprot/Q50KZ9.html
• Entrez gene: http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&cmd=Retrieve&dopt=Graphics&list_uids=338396