glucose transporter-10; GLUT10; solute carrier family 2 member 10; SLC2A10; facilitated glucose transporter

Function

• facilitative glucose transporter

Kinetic parameters: KM=0.28 mM for 2-deoxy-D-glucose

Structure

• belongs to the major facilitator superfamily, sugar transporter (TC 2.A.1.1) family, glucose transporter subfamily

Compartment

• intracytoplasmic membrane
• cytoplasm, perinuclear region

Expression

• widely expressed
• highest levels in liver & pancreas

Pathology

• defects in SLC2A10 are the cause of arterial tortuosity syndrome

More general terms

• glucose transporter
• transmembrane 12 protein
• solute carrier family 2 (SLC2, SLC2A)

Database

• Kegg: http://www.genome.jp/dbget-bin/www_bget?hsa:8103
• OMIM: https://mirror.omim.org/entry/208050
• OMIM: https://mirror.omim.org/entry/606145
• UniProt: http://www.uniprot.org/uniprot/O95528.html