low-density lipoprotein receptor-related protein 4; multiple epidermal growth factor-like domains 7 (LRP4, KIAA0816, MEGF7)

Function

• cell surface endocytic receptor
• binds & internalizes extracellular ligands for degradation by lysosomes

Structure

• belongs to the LDLR family
• contains 3 EGF-like domains
• contains 8 LDL-receptor class A domains
• contains 20 LDL-receptor class B repeats

Compartment

membrane

Expression

expressed in several regions of the brain

More general terms

• low-density lipoprotein (LDL) receptor related protein (LRP)
• multiple epidermal growth factor like domains (protein)

Database

• OMIM: https://mirror.omim.org/entry/604270
• UniProt: http://www.uniprot.org/uniprot/O75096.html
• Entrez gene: http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&cmd=Retrieve&dopt=Graphics&list_uids=4038