pregnancy-specific beta-1-glycoprotein 1; PS-beta-G-1; PSBG-1; pregnancy-specific glycoprotein 1; CD66 antigen-like family member F; fetal liver non-specific cross-reactive antigen 1/2; FL-NCA-1/2; PSG95; pregnancy-specific beta-1 glycoprotein C/D; PS-beta-C/D; CD66f (PSG1, B1G1, PSBG1, PSGGA)

Function

• may be involved in immune regulation, protection of fetus from maternal immune system

Structure

• belongs to the immunoglobulin superfamily, CEA family
• contains 3 Ig-like C2-type domains
• contains 1 Ig-like V-type domain

Compartment

secreted (putative)

Alternative splicing

named isoforms=4

Expression

• detectable in serum in 1st 2-3 weeks of pregnancy
• produced in high quantity during pregnancy
• syncytiotrophoblasts
• fetal liver
• myeloid cell lines

More general terms

• pregnancy-specific beta-1-glycoprotein
• CD antigen

Database

• Entrez gene: http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&cmd=Retrieve&dopt=Graphics&list_uids=5669
• Kegg: http://www.genome.jp/dbget-bin/www_bget?hsa:5669
• OMIM: https://mirror.omim.org/entry/176390
• UniProt: http://www.uniprot.org/uniprot/P11464.html