angiopoietin-4; ANG-4; angiopoietin-3; ANG-3 (ANGPT4, ANG3, ANG4)

Function

• binds to tyrosine-protein kinase receptor TIE2 & activates it

Structure

contains 1 fibrinogen C-terminal domain

Compartment

secreted (probable)

Expression

• highly expressed in the lung
• much lower levels found in other tissues

More general terms

• angiopoietin
• secreted protein

Database

• Entrez gene: http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&cmd=Retrieve&dopt=Graphics&list_uids=51378
• Kegg: http://www.genome.jp/dbget-bin/www_bget?hsa:51378
• OMIM: https://mirror.omim.org/entry/603705
• UniProt: http://www.uniprot.org/uniprot/Q9Y264.html