testisin; eosinophil serine protease 1; ESP-1; serine protease 21 (PRSS21, ESP1, TEST1, UNQ266/PRO303)

Function

• may regulate proteolytic events associated with testicular germ cell maturation

Structure

• belongs to the peptidase S1 family
• contains 1 peptidase S1 domain

Compartment

• cell membrane; lipid-anchor, GPI-anchor

Alternative splicing

named isoforms=3

Expression

• expressed predominantly in premeiotic testicular germ cells, mostly late pachytene & diplotene spermatocytes

More general terms

• serine protease
• glypiated protein
• testis-specific protein

Database

• Entrez gene: http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&cmd=Retrieve&dopt=Graphics&list_uids=10942
• Kegg: http://www.genome.jp/dbget-bin/www_bget?hsa:10942
• OMIM: https://mirror.omim.org/entry/608159
• UniProt: http://www.uniprot.org/uniprot/Q9Y6M0.html