endomucin (endothelial sialomucin, mucin-like sialoglycoprotein, endomucin-2, mucin-14, gastric cancer antigen Ga34, EMCN, EMCN2, MUC14)

Function

• interferes with assembly of focal adhesion complexes
• inhibits interaction between cells & extracellular matrix

Structure

• highly O-glycosylated
• sialic acid-rich glycoprotein

Compartment

• isoform 1: cell membrane
• isoform 2: secreted
• consistently localized to plasma membrane & less abundantly to Golgi-like perinuclear stacks

Alternative splicing

named isoforms=2

Expression

• expressed in heart, kidney, lung

More general terms

• sialoglycoprotein
• mucin

Database

• OMIM: https://mirror.omim.org/entry/608350
• UniProt: http://www.uniprot.org/uniprot/Q9ULC0.html