acidic leucine-rich nuclear phosphoprotein 32 member C; phosphoprotein 32-related protein 1; tumorigenic protein pp32r1 (ANP32C, PP32R1)

Structure

• belongs to the ANP32 family
• contains 4 LRR repeats (leucine-rich repeats)
• although classified as a phosphoprotein, no phosphorylation sites are identified

Expression

• expressed in activated stem cells, such as mobilized CD34+ cells & cord blood CD34+ cells, but not in resting bone marrow CD34+ cells
• expressed in a variety of neoplastic cell lines, mainly in prostatic adenocarcinoma cell lines
• not expressed in normal prostatic tissue

Notes

• His-140 polymorphism is uncertain

More general terms

• acidic leucine-rich nuclear phosphoprotein 32 (ANP32)

Database

• Entrez gene: http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&cmd=Retrieve&dopt=Graphics&list_uids=23520
• Kegg: http://www.genome.jp/dbget-bin/www_bget?hsa:23520
• OMIM: https://mirror.omim.org/entry/606877
• UniProt: http://www.uniprot.org/uniprot/O43423.html