gamma-aminobutyric acid receptor subunit alpha-2; GABA(A) receptor subunit alpha-2 (GABRA2)
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Function
- GABA-A receptor alpha subunit
- binds UBQLN1 (putative)
- anxiolytic benzodiazepine receptor may depend upon GABA-A receptor alpha-2.
Structure
Compartment
Polymorphism
- genetic variations in GABRA2 determine the genetic susceptibility to alcoholism[4]
More general terms
References
- ↑ UniProt http://www.uniprot.org/uniprot/P47869.html
- ↑ Protein Spotlight; Note: forbidden fruit - Issue 56 of March 2005 http://www.expasy.org/spotlight/back_issues/sptlt056.shtml
- ↑ Journal Watch 20(22):176, 2000 Low K, Crestani F, Keist R, Benke D, Brunig I et al Molecular and neuronal substrate for the selective attenuation of anxiety. Science. 2000 Oct 6;290(5489):131-4. Erratum in: Science 2000 Nov 3;290(5493):936c. PMID: https://www.ncbi.nlm.nih.gov/pubmed/11021797
- ↑ 4.0 4.1 OMIM https://mirror.omim.org/entry/103780