integrator complex subunit 11 (Int11, INTS11, CPSF3L-like protein, protein related to CPSF subunits of 68 kD, RC-68, CPSF3L, RC68)

Function

• catalytic component of the Integrator complex
• mediates the snRNAs 3' cleavage
• HXHXDH motif essential for the endoribonuclease activity

Compartment

nucleus, cytoplasm

Alternative splicing

named isoforms=3

More general terms

• enzyme catalytic subunit
• endoribonuclease
• zinc finger protein

Component of

• integrator complex (multiprotein complex integrator)

Database

• UniProt: http://www.uniprot.org/uniprot/Q5TA45.html