OTU domain-containing protein 7A; zinc finger protein Cezanne 2 (OTUD7A, C15orf16, OTUD7)

Function

• deubiquitinating activity directed towards Lys-48 or Lys-63-linked polyubiquitin chains
• hydrolyzes both linear & branched forms of polyubiquitin

Structure

• belongs to the peptidase C64 famil
• contains 1 A20-type zinc finger
  • contains 1 OTU domain

Compartment

cytoplasm, nucleus

Alternative splicing

named isoforms=2

More general terms

• cysteine proteinase; thiol proteinase
• zinc finger protein
• OTU domain-containing protein (OTUD)

Database

• UniProt: http://www.uniprot.org/uniprot/Q8TE49.html