sharpin (shank-associated RH domain-interacting protein, shank-interacting protein-like 1, hSIPL1, SIPL1, PSEC0216)

Function

• self-associates
• interacts with SHANK1

Structure

contains 1 RanBP2-type zinc finger

Compartment

• cytoplasm
• enriched at synaptic sites in mature neurons where it colocalizes with SHANK1

Alternative splicing

named isoforms=3

Expression

• expressed in skeletal muscle & placenta > brain, heart, colon without mucosa, thymus, spleen, kidney, liver, small intestine, lung, peripheral blood leukocytes

More general terms

• zinc finger protein

Database

• UniProt: http://www.uniprot.org/uniprot/Q9H0F6.html