zinc finger protein 294; E3 ubiquitin-protein ligase listerin; RING finger protein 160 (LTN1, C21orf10, C21orf98, KIAA0714, RNF160, ZNF294, HSPC087)

Function

• E3 ubiquitin-protein ligase
• E3 ubiquitin ligases accept ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester & then directly transfer the ubiquitin to targeted substrates (putative)
• protein modification; protein ubiquitination
• autoubiquitinated (putative)

Structure

• belongs to the LTN1 family
• contains 1 RING-type Zn+2 finger

Alternative splicing

named isoforms=2

More general terms

• E3 ubiquitin ligase
• ring finger protein
• phosphoprotein

Database

• Entrez gene: http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&cmd=Retrieve&dopt=Graphics&list_uids=26046
• Kegg: http://www.genome.jp/dbget-bin/www_bget?hsa:26046
• OMIM: https://mirror.omim.org/entry/613083
• UniProt: http://www.uniprot.org/uniprot/O94822.html