pyruvate dehydrogenase phosphatase catalytic subunit 2; [pyruvate dehydrogenase [acetyl-transferring]]-phosphatase 2, mitochondrial; PDP 2; PDPC 2 (PDP2, KIAA1348)

Function

• catalyzes the dephosphorylation & concomitant reactivation of pyruvate dehydrogenase E1-alpha (putative)
• component of pyruvate dehydrogenase phosphatase, heterodimer of an enzyme catalytic subunit (PDP2) & an a FAD protein of unknown function

[pyruvate dehydrogenase (acetyl-transferring)]phosphate + H2O = [pyruvate dehydrogenase (acetyl-transferring)] + phosphate

Cofactor: binds 2 Mg+2 per subunit (putative)

Structure

belongs to the PP2C family

Compartment

mitochondrial matrix (putative)

More general terms

• pyruvate dehydrogenase phosphatase catalytic subunit

Database

• Entrez gene: http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&cmd=Retrieve&dopt=Graphics&list_uids=57546
• Kegg: http://www.genome.jp/dbget-bin/www_bget?hsa:57546
• UniProt: http://www.uniprot.org/uniprot/Q9P2J9.html