pygopus homolog 1 (PYGO1)

Function

• role in signal transduction through the Wnt pathway
• binds to BCL9 via the PHD-type Zn+2 finger motif, & becomes part of the nuclear beta-catenin/TCF complex
• found in a complex with BCL9L, CDC73, CTNNB1 & PYGO1

Structure

contains 1 PHD-type Zn+2 finger

Compartment

nucleus (probable)

More general terms

• pygopus homolog
• zinc finger protein

Database

• Entrez gene: http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&cmd=Retrieve&dopt=Graphics&list_uids=26108
• Kegg: http://www.genome.jp/dbget-bin/www_bget?hsa:26108
• OMIM: https://mirror.omim.org/entry/606902
• UniProt: http://www.uniprot.org/uniprot/Q9Y3Y4.html