high mobility group protein B3; high mobility group protein 4; HMG-4; high mobility group protein 2a; HMG-2a (HMGB3, HMG2A, HMG4)

Function

• binds preferentially single-stranded DNA
• unwinds double stranded DNA (putative)

Structure

• belongs to the HMGB family
• contains 2 HMG box DNA-binding domains

Compartment

nucleus (putative)

Expression

expressed predominantly in placenta

More general terms

• high-mobility group [HMG] protein
• DNA-binding protein
• nonhistone chromosomal protein

Database

• Entrez gene: http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&cmd=Retrieve&dopt=Graphics&list_uids=3149
• Kegg: http://www.genome.jp/dbget-bin/www_bget?hsa:3149
• OMIM: https://mirror.omim.org/entry/300193
• UniProt: http://www.uniprot.org/uniprot/O15347.html