DNA polymerase mu (POLM)

Function

• seems to act as an Ig mutase responsible for immunoglobulin (Ig) gene hypermutation

Cofactor: Mg+2 (putative)

Structure

• belongs to the DNA polymerase type-X family
• contains 1 BRCT domain

Compartment

nucleus (putative)

Expression

• expressed in a number of tissues
• abundant in thymus

More general terms

• DNA polymerase

Database

• Kegg: http://www.genome.jp/dbget-bin/www_bget?hsa:2743
• OMIM: https://mirror.omim.org/entry/606344
• UniProt: http://www.uniprot.org/uniprot/Q9NP87.html