single-stranded DNA-binding protein 3 (sequence-specific single-stranded-DNA-binding protein, SSBP3, SSDP, SSDP1)
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Function
- role in transcription regulation of collagen-1 alpha-2 gene where it binds to single-stranded polypyrimidine sequences in the promoter region
Structure
- contains 1 LisH domain
Compartment
Alternative splicing
named isoforms=3
Expression
- highly expressed in all hematopoietic tissues, including spleen, lymph node, peripheral blood, bone marrow, thymus, & fetal liver
- highest expression in thymus & fetal liver
- expression is also high in heart, brain, kidney, & skeletal muscle