nuclear factor erythroid 2-related factor 3; NF-E2-related factor 3; NFE2-related factor 3; nuclear factor, erythroid derived 2, like 3 (NFE2L3, NRF3)

Function

• activates erythroid-specific, globin gene expression
• heterodimer with MAFG, MAFK & other small MAF proteins that bind to MAF recognition elements (MARE)

Compartment

nucleus

Expression

• highly expressed in human placenta, B-cell & monocyte cell lines
• low expression in heart, brain, lung, skeletal muscle, kidney, pancreas

More general terms

• DNA-binding protein

Database

• Entrez gene: http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&cmd=Retrieve&dopt=Graphics&list_uids=9603
• Kegg: http://www.genome.jp/dbget-bin/www_bget?hsa:9603
• OMIM: https://mirror.omim.org/entry/604135
• UniProt: http://www.uniprot.org/uniprot/Q9Y4A8.html