protein S100-A3; S100 Ca+2-binding protein A3; protein S-100E (S100A3 S100E)

Function

• binds both Ca+2 & Zn+2
• probably binds 2 Zn+2 per molecule
• role in Ca+2-dependent cuticle cell differentiation & hair shaft formation (putative)

Structure

• homodimer
• belongs to the S-100 family
• contains 2 EF-hand domains

Expression

skin specific

More general terms

• S100 Ca+2-binding protein A

Additional terms

• S100 Ca+2-binding protein

Database

• UniProt: http://www.uniprot.org/uniprot/P33764.html
• Entrez gene: http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&cmd=Retrieve&dopt=Graphics&list_uids=6274
• Kegg: http://www.genome.jp/dbget-bin/www_bget?hsa:6274
• OMIM: https://mirror.omim.org/entry/176992