endoplasmic reticulum protein ER60; PDIA3; protein disulfide isomerase A3; 58 kD microsomal protein; 58 kDa glucose regulated protein (ERp57, ERp60)

Function

• interacts with ERP27
• catalyzes the rearrangement of -S-S- bonds in proteins

Structure

• belongs to the protein disulfide isomerase family
• contains 2 thioredoxin domains

Compartment

• endoplasmic reticulum lumen (putative)
• melanosome

Notes

• originally thought to be a phospholipase C-alpha

More general terms

• protein disulfide isomerase

Database

• UniProt: http://www.uniprot.org/uniprot/P30101.html
• Kegg: http://www.genome.jp/dbget-bin/www_bget?hsa:2923
• OMIM: https://mirror.omim.org/entry/602046