phospholipase C-alpha

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Introduction

A major isozyme of mammalian liver; insensitive to Ca+2.

More general terms

References

  1. Dennis EA, Rhee SG, Billah MM, Hannun YA. Role of phospholipase in generating lipid second messengers in signal transduction. FASEB J. 1991 Apr;5(7):2068-77. Review. PMID: https://www.ncbi.nlm.nih.gov/pubmed/1901288
  2. Taylor SJ, Chae HZ, Rhee SG, Exton JH. Activation of the beta 1 isozyme of phospholipase C by alpha subunits of the Gq class of G proteins. Nature. 1991 Apr 11;350(6318):516-8. PMID: https://www.ncbi.nlm.nih.gov/pubmed/1707501