macropain MECL-1; proteasome subunit beta type-10; proteasome MECL-1; multicatalytic endopeptidase complex subunit MECl-1 (PSMB10, MECL1)

Function

• component of the 20S proteasome which is a component of the 26S proteasome
• PSMB10 is part of the immunoproteasome where it displaces the equivalent houskeeping subunit PSMB7

Structure

belongs to the peptidase T1B family

Compartment

cytoplasm (putative), nucleus

Expression

induced by interferon gamma

More general terms

• macropain-beta subunit

Component of

• 20S proteasome

Database

• UniProt: http://www.uniprot.org/uniprot/P40306.html
• Kegg: http://www.genome.jp/dbget-bin/www_bget?hsa:5699
• OMIM: https://mirror.omim.org/entry/176847