eukaryotic initiation factor 3 subunit 8 (eukaryotic translation initiation factor 3 subunit C, eIF3 p110, eIF3c, EIF3S8, eIF-3s8)

Function

• binds to the 40S ribosome & promotes the binding of methionyl-tRNAi & mRNA
• eIF-3 is composed of at least 13 different subunits
• interacts with EIF3K

Structure

• belongs to the eIF-3 subunit C family
• contains 1 PCI domain

More general terms

• eukaryotic initiation factor subunit

Component of

• eukaryotic initiation factor 3; ribosome dissociation factor (eIF3)

Database

• Kegg: http://www.genome.jp/dbget-bin/www_bget?hsa:7286
• Kegg: http://www.genome.jp/dbget-bin/www_bget?hsa:8663
• OMIM: https://mirror.omim.org/entry/603916
• UniProt: http://www.uniprot.org/uniprot/Q99613.html