26S proteasome regulatory subunit S14 (26S proteasome non-ATPase regulatory subunit 8, 26S proteasome subunit p31, PSMD8)

Function

• regulatory subunit of the 26S proteasome
• involved in the ATP-dependent degradation of ubiquitinated proteins
• necessary for activation of the CDC28 kinase

Structure

belongs to the proteasome subunit S14 family

More general terms

• 26S proteasome subunit

Component of

• 19S proteasome (PA700 complex)

Database

• Kegg: http://www.genome.jp/dbget-bin/www_bget?hsa:5714
• UniProt: http://www.uniprot.org/uniprot/P48556.html