N-terminal acetyltransferase complex ARD1 subunit homolog B; hARD2 (ARD1B, ARD2, NAA11)

Function

• in complex with NARG1, displays alpha (N-terminal) acetyltransferase activity
• interacts with NARG1 & HIF1A

Acetyl-CoA + peptide <--> N(alpha)-acetylpeptide + CoA

Structure

• belongs to the acetyltransferase family, ARD1 subfamily
• contains 1 N-acetyltransferase domain

Compartment

cytoplasm, nucleus

Expression

• present in several cell lines, with highest levels in MCF-7 cells (at protein level)

More general terms

• enzyme catalytic subunit

Database

• UniProt: http://www.uniprot.org/uniprot/Q9BSU3.html