LDL cholesterol direct (LDL direct) in serum

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Introduction

Used in conjunction with Synchron LX systems, Unicel DxC 600/800 systems.

Indications

hypertriglyceridemia

Principle

Detergent 1
                    cholesterol esterase
HDL-C, VLDL-C, CM-C -------------------->   non color poduct
                    cholesterol oxidase
Detergent 2
                 cholesterol esterase
LDL cholesterol  -------------------->  cholestenone + H2O2
                 cholesterol oxidase
                        peroxidase
H2O2 + DSBmT* + 4-AA*   ------------>    color product

* DSBmT = N,N-bis (4-sulphobutyl)-m-toluidine-disodium 4-AA = 4 aminopyrine

Increases

More general terms

Additional terms

References

  1. Veterans Administration