Ras association domain-containing protein 8; carcinoma-associated protein HOJ-1 (RASSF8, C12orf2)

Structure

• contains 1 Ras-associating domain

Alternative splicing

named isoforms=2

Expression

• widely expressed as a 6.2 kb transcript
• a 2.2 kb alternatively spliced transcript is expressed exclusively in testis

Pathology

• chromosomal translocation involving RASSF8 t(12;22)(p11.2;q13.3) with FBLN1 is found in a complex type of synpolydactyly

More general terms

• Ras association domain-containing protein (RASSF)

Database

• OMIM: https://mirror.omim.org/entry/608180
• OMIM: https://mirror.omim.org/entry/608231
• UniProt: http://www.uniprot.org/uniprot/Q8NHQ8.html