anti-laminaribioside antibody
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Introduction
Etiology
Clinical significance
- associated with Crohn's disease
- 44% of anti-Saccharomyces cerevisiae antibody-negative Crohn's disease positive for antilaminaribioside or antichitobioside
- in patients with inflammatory bowel disease, detection of 2 of 3 antibodies:
- anti-laminaribioside
- anti-chitobioside
- anti-mannan is 99% specific for Crohn's disease
- higher titers of anti-laminaribioside or anti-mannan associated with small intestinal disease
More general terms
Additional terms
- Crohn's disease; terminal ileitis; regional enteritis; granulomatous enteritis; chronic cicatrizing enteritis
- laminaribioside
References
- ↑ Dotan I, Fishman S, Dgani Y, Schwartz M, Karban A, Lerner A, Weishauss O, Spector L, Shtevi A, Altstock RT, Dotan N, Halpern Z. Antibodies against laminaribioside and chitobioside are novel serologic markers in Crohn's disease. Gastroenterology. 2006 Aug;131(2):366-78. PMID: https://www.ncbi.nlm.nih.gov/pubmed/16890590