anti-chitobioside antibody
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Introduction
Antibody to chitobioside.
Etiology
Clinical significance
- associated with Crohn's disease
- 44% of anti-Saccharomyces cerevisiae antibody-negative Crohn's disease positive for antilaminaribioside or antichitobioside
- in patients with inflammatory bowel disease, detection of 2 of 3 antibodies
- anti-laminaribioside
- anti-chitobioside
- anti-mannan is 99% specific for Crohn's disease
More general terms
Additional terms
- chitobioside
- Crohn's disease; terminal ileitis; regional enteritis; granulomatous enteritis; chronic cicatrizing enteritis
References
- ↑ Dotan I, Fishman S, Dgani Y, Schwartz M, Karban A, Lerner A, Weishauss O, Spector L, Shtevi A, Altstock RT, Dotan N, Halpern Z. Antibodies against laminaribioside and chitobioside are novel serologic markers in Crohn's disease. Gastroenterology. 2006 Aug;131(2):366-78. PMID: https://www.ncbi.nlm.nih.gov/pubmed/16890590