WD repeat domain phosphoinositide-interacting protein 4 (WIPI-4, WD repeat protein 45, WDR45, WDRXI4, WIPI4, JM5)
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Structure
contains 3 WD repeats
Alternative splicing
named isoforms=3
Expression
- ubiquitously expressed
- expressed in skeletal muscle, heart > liver, placenta
Pathology
- expression is down-regulated in pancreatic cancer & kidney cancer