WD repeat-containing protein 39; cytosolic iron-sulfur protein assembly protein CIAO1 (CIAO1, WDR39)

Function

• component of the cytosolic iron-sulfur (Fe/S) protein assembly machinery
• required for maturation of extramitochondrial Fe/S proteins
• seems to specifically modulate transactivation activity of WT1

Structure

• belongs to the WD repeat CIA1 family
• contains 7 WD repeats

Notes

• 'Ciao' means 'bridge' in chinese
• interacts with WT1

More general terms

• WD repeat protein family

Database

• Entrez gene: http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&cmd=Retrieve&dopt=Graphics&list_uids=9391
• Kegg: http://www.genome.jp/dbget-bin/www_bget?hsa:9391
• OMIM: https://mirror.omim.org/entry/604333
• UniProt: http://www.uniprot.org/uniprot/O76071.html