protein phosphatase Slingshot homolog 2; SSH-2L; hSSH-2L (SSH2, KIAA1725, SSH2L)

Function

• regulates actin filament dynamics
• dephosphorylates & activates cofilin (disassembles actin); (LIMK1 phosphorylates & deactivates cofilin)

Structure

• belongs to the protein-tyrosine phosphatase family
• contains 1 tyrosine-protein phosphatase domain

Compartment

cytoplasm, cytoskeleton

Alternative splicing

named isoforms=4

More general terms

• protein phosphatase Slingshot homolog (ssH)

Database

• OMIM: https://mirror.omim.org/entry/606779
• Entrez gene: http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&cmd=Retrieve&dopt=Graphics&list_uids=85464
• Kegg: http://www.genome.jp/dbget-bin/www_bget?hsa:85464
• UniProt: http://www.uniprot.org/uniprot/Q76I76.html